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Implement eBR faster. Digitize batch documentation cleanly. - Hintergrundbild

Implement eBR faster. Digitize batch documentation cleanly.

When batch documentation is still paper-based or changes in existing eBR and MES structures take too long, an operational and regulatory bottleneck emerges. anicomply helps pharmaceutical manufacturers, CMOs and CDMOs transform existing SOPs and Word-based manufacturing instructions into executable, validatable eBR workflows in record time: when processes, reviews and test basis are prepared, a fully validatable pilot can be up and running within just two weeks! This makes digitization usable faster without losing regulatory robustness.

Challenges in Pharma & Life Sciences – solved with anicomply eBR

Flexibility

Problem

  • Volatile demand and uncertain markets
  • Frequent changes to formulations and processes
  • Small batch sizes and short product life cycles

Solution with anicomply (eBR)

  • Flexible, electronic batch records
  • Controlled adjustments without media breaks
  • GMP-compliant documentation even with frequent changes

Complexity

Problem

  • Complex manufacturing processes with many dependencies
  • High product variety and batch-specific workflows
  • Increasing documentation and traceability requirements

Solution with anicomply (eBR)

  • Structured, batch-based eBRs
  • Clear guidance through complex manufacturing processes
  • Complete traceability of all steps

Digitalization

Problem

  • Paper-based batch records
  • Media breaks between production, QA and IT
  • High manual effort and error susceptibility

Solution with anicomply (eBR)

  • Fully digital batch record
  • Integration of process and production data
  • "Right-First-Time" through guided workflows

Transparency

Problem

  • Fragile supply chains and API dependencies
  • High audit and inspection pressure
  • Time-consuming investigation of deviations

Solution with anicomply (eBR)

  • Central, tamper-proof batch history
  • Direct access to all relevant data
  • Audit readiness at the push of a button

Speed

Problem

  • Long review and release cycles
  • Tight launch windows
  • Delays due to rework and corrections

Solution with anicomply (eBR)

  • Automatic checks during manufacturing
  • Review by Exception
  • Faster batch release and shorter time-to-market

Efficiency

Problem

  • High economic pressure
  • Costs from errors, rework and paper
  • Limited scalability across sites

Solution with anicomply (eBR)

  • Reduced manufacturing and quality costs
  • Fewer deviations and rework
  • Scalable eBR platform for global production
Challenges in Pharma & Life Sciences – solved with anicomply eBR

anicomply turns manufacturing complexity into a digital, manageable process – as eBR software for modern pharma production.

CDMO/CMO Requirements & Data Exchange

CDMOs/CMOs must not only manufacture but also ensure seamless, near real-time data exchange with clients. As a result, technological capabilities, modern interfaces, and digital data transfer are becoming increasingly important.

Reduced Validation Complexity in GxP Environments Through the anicomply Declarative Recipe Model

We bring the workflow to where the content already lives – instead of imposing a new modeling paradigm.

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Regulatory Requirements & Digitalization

Regulatory bodies like EMA and FDA are increasingly demanding the digitalization of manufacturing processes.
The goal is higher product quality, better data integrity, and complete traceability.

Need for Flexible Production Systems

Rapid scaling, lower investment risks, higher resilience with anicomply

From paper chaos to a fast eBR entry

Why traditional systems slow you down and how anicomply shortens the entry

Yesterday

The struggle with paper

  • Months to years for recipe changes
  • Manual transfers and media breaks
  • Endless validation cycles
  • High error rates and frustrated teams

Today

Digital bottleneck

  • Weeks for simple changes
  • External specialists and modeling effort
  • Vendor lock-in ("golden cage")
  • Little room for maneuver with tightly managed budgets

Tomorrow

Focused entry with anicomply

  • SOP to workflow in minutes through Word-native eBR
  • 90–100% changes without vendor
  • eBR-first instead of full MES project
  • Integration with SCADA/OT, ERP and MES as needed

Tomorrow: Push-button manufacturing with anicomply

Imagine a world where you create and release new, validated recipes in minutes instead of weeks.
anicomply is the lightweight, agile eBR system that meets the requirements of Industry 4.0:

  • SOP to workflow in minutes: Use Microsoft Word® as the familiar editor to design production workflows intuitively.
  • Customizable approval processes: Define your own review and approval workflows – simple and digital.
  • Available on any device: Access your recipes from anywhere, whether in the office or directly on the production line.
  • Seamless documentation without effort: anicomply provides automatic version and change tracking that convinces any auditor.
  • Economical entry instead of large-scale project: Benefits become visible early, without having to finance a months-long full program right away.
  • GxP-compliant process guidance: Audit trail, versioning, electronic signatures and traceable approvals are built in from the start.
  • Integration as needed: SCADA, ERP and MES-adjacent systems can be connected step by step.

What makes anicomply different

SOP instead of rebuild

Existing Word and SOP structures are used rather than re-modeling processes from scratch.

Pilot instead of large-scale project

Early visible operational usability replaces long lead times without clear added value.

Validatable from the start

Changes remain regulatory robust and manageable from a project perspective.

eBR-first with integration path

Companies can start specifically with batch documentation and expand later.

Electronic Batch Record (eBR) Software Comparison

Criterion (semantic keywords) Classic MES (eBR‑module) Generic Low‑Code App Builder anicomply (Word‑native eBR‑platform)
Change cycle time (recipe change speed) Weeks–Months Days–Weeks Within one day for workflow conversion
Modeling effort (workflow authoring) Specialist training & vendor scripting Abstract visual modeling canvas Familiar Microsoft Word® document structuring
Audit trail & 21 CFR Part 11 Partially add-on / fragmented Limited / custom scripts Native audit trail + electronic signatures
Vendor lock / portability High (proprietary data model) Medium Low – existing Word-based source assets remain usable
Domain autonomy (domain-driven changes) Low (external specialists) Medium High – changes remain domain-driven and quickly implementable
Validation overhead (cycle reduction potential) High (rebuild & regression) Medium Reduced – focused eBR entry with manageable scope
GxP compliance alignment Broad, but cumbersome rollout Generic, requires customization Pre-shaped for GxP / Part 11 from the start
Learning curve (time to productivity) Long (training cycles) Medium Short – leverages existing Word skills
Total Cost of Ownership (TCO drivers) Licenses + customization services Platform + internal configuration time Less modeling and change effort with early time-to-value
Upgrade friction (version changes) High (dependency cascade) Medium Low – focused eBR layer instead of monolithic expansion

How a regulated manufacturer made batch documentation digitally usable without a large-scale project

Pharma 4.0 is fundamentally transforming production: smaller batches, faster adaptation to market needs, and a variety of products on a single line. With anicomply, the breakthrough was achieved: processes were digitized in compliance with GxP, compliance was ensured, and at the same time an economically tangible entry into eBR was created.

Frequently asked questions about implementation, validation and integration

Audit trail, versioning, electronic signatures and traceable approval processes are core features. This enables anicomply to support use in GxP-regulated environments while keeping the change and validation effort within a manageable scope.

anicomply is primarily an eBR-first solution for digital batch documentation and workflow-driven process execution. For companies that primarily need a robust eBR, this can already cover the central requirement. In more complex environments, anicomply can be integrated into existing SCADA, ERP or MES-adjacent landscapes.

Existing SOPs or Word-based recipe documents can be digitized into digital eBR workflows with anicomply within a few hours. When processes, reviews and test basis are prepared, a validatable pilot can be ready in about two weeks. The broader productive entry typically occurs within up to 3 months, depending on integrations and validation scope.

anicomply is especially relevant for companies with paper-based or hybrid batch documentation, for CMO/CDMO with frequent changes and varying customer requirements, and for small to mid-sized pharmaceutical manufacturers who initially need a robust eBR without immediately starting a full MES project.

Because anicomply converts existing SOPs and Word structures directly into executable workflows, rather than redirecting domain experts to abstract modeling canvases. This reduces modeling effort, accelerates changes and makes the business value visible faster.